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Leptin signaling and leptin resistance
Yingjiang Zhou, Liangyou Rui
Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 207-222 doi: 10.1007/s11684-013-0263-5
Leptin is secreted into the bloodstream by adipocytes and is required for the maintenance of energyLeptin deficiency or genetic defects in the components of the leptin signaling pathways cause obesityLeptin controls energy balance and body weight mainly through leptin receptor b (LEPRb)-expressing neuronsLeptin resistance is the key risk factor for obesity.This review is focused on recent advance about leptin action, leptin signaling, and leptin resistance
Keywords: leptin signaling leptin receptor energy balance leptin resistance obesity
Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene
Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG
Frontiers of Medicine 2009, Volume 3, Issue 1, Pages 57-60 doi: 10.1007/s11684-009-0003-z
Keywords: receptors leptin RNA interference lentivirus vector
XIA Dasheng, SONG Yanqiu, LI Chao, ZHANG Feng, WEI Minxin
Frontiers of Medicine 2007, Volume 1, Issue 4, Pages 352-355 doi: 10.1007/s11684-007-0067-6
Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases
Chong Liu, Dingfeng Su
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 35-40 doi: 10.1007/s11684-012-0171-0
Keywords: α7 nicotinic acetylcholine receptor cardiovascular diseases baroreflex sensitivity
Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels
LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie
Frontiers of Medicine 2007, Volume 1, Issue 1, Pages 87-92 doi: 10.1007/s11684-007-0017-3
Keywords: significant difference intestinal I/R transcriptase-polymerase metabolic central secretory
Peter B. Alexander,Xiao-Fan Wang
Frontiers of Medicine 2015, Volume 9, Issue 2, Pages 134-138 doi: 10.1007/s11684-015-0396-9
Keywords: targeted therapy drug resistance receptor tyrosine kinases cancer
Wenjie Zhu, Binghe Xu
Frontiers of Medicine 2021, Volume 15, Issue 2, Pages 208-220 doi: 10.1007/s11684-020-0795-4
Keywords: endocrine-resistant HR+/HER2- advanced breast cancer randomized clinical trials meta-analysis targeted therapy
Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 699-713 doi: 10.1007/s11684-022-0972-8
Keywords: anti-CD19 chimeric antigen receptor T immunotherapy diffuse large B cell lymphoma tumor microenvironment
Chimeric antigen receptor T cell therapies for acute myeloid leukemia
Bin Gu, Jianhong Chu, Depei Wu
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 701-710 doi: 10.1007/s11684-020-0763-z
Keywords: acute myeloid leukemia CAR T immunotherapy
Chimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy
Zhao Zhang, Jun Jiang, Xiaodong Wu, Mengyao Zhang, Dan Luo, Renyu Zhang, Shiyou Li, Youwen He, Huijie Bian, Zhinan Chen
Frontiers of Medicine 2019, Volume 13, Issue 1, Pages 57-68 doi: 10.1007/s11684-019-0683-y
Keywords: chimeric antigen receptor T cells epidermal growth factor receptor lung cancer immunotherapy tumor immunolog
Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages
LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao
Frontiers of Medicine 2008, Volume 2, Issue 2, Pages 166-170 doi: 10.1007/s11684-008-0030-1
Changlin Cao, Jingxian Gu, Jingyao Zhang
Frontiers of Medicine 2017, Volume 11, Issue 2, Pages 169-177 doi: 10.1007/s11684-017-0505-z
Keywords: soluble triggering receptor expressed on myeloid cells-1 infectious diseases diagnosis and prognosis
Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 309-315 doi: 10.1007/s11684-009-0043-4
Keywords: graft vs host disease proteinase-activated receptor murine model hematopoietic stem cell transplantation
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Frontiers of Medicine 2020, Volume 14, Issue 6, Pages 711-725 doi: 10.1007/s11684-020-0808-3
Keywords: chimeric antigen receptor T (CAR-T) cell lymphoma cytokine release syndrome (CRS) immune effector cell-associated
XU Aijun, TIAN Yuke, DUAN Shiming
Frontiers of Medicine 2007, Volume 1, Issue 2, Pages 207-210 doi: 10.1007/s11684-007-0039-x
Title Author Date Type Operation
Construction and identification of lentiviral RNA interference vector of rat leptin receptor gene
Zhengjuan LIU, Jie BIAN, Yuchuan WANG, Yongli ZHAO, Dong YAN, Xiaoxia WANG
Journal Article
The change of serum leptin and its relationship with platelet membrane glycoprotein Ib in patients with
XIA Dasheng, SONG Yanqiu, LI Chao, ZHANG Feng, WEI Minxin
Journal Article
Nicotinic acetylcholine receptor α7 subunit: a novel therapeutic target for cardiovascular diseases
Chong Liu, Dingfeng Su
Journal Article
Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels
LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie
Journal Article
Resistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategies
Peter B. Alexander,Xiao-Fan Wang
Journal Article
Overcoming resistance to endocrine therapy in hormone receptor-positive human epidermal growth factorreceptor 2-negative (HR
Wenjie Zhu, Binghe Xu
Journal Article
microenvironment contributes to tumor progression in diffuse large B-cell lymphoma upon anti-CD19 chimeric antigen receptor
Journal Article
Chimeric antigen receptor T cell therapies for acute myeloid leukemia
Bin Gu, Jianhong Chu, Depei Wu
Journal Article
Chimeric antigen receptor T cell targeting EGFRvIII for metastatic lung cancer therapy
Zhao Zhang, Jun Jiang, Xiaodong Wu, Mengyao Zhang, Dan Luo, Renyu Zhang, Shiyou Li, Youwen He, Huijie Bian, Zhinan Chen
Journal Article
Blockage of receptor-interacting protein 2 expression by small interfering RNA in murine macrophages
LIU Hongchun, CAO Zhongwei, JIN Jianjun, WANG Jiyao
Journal Article
Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis
Changlin Cao, Jingxian Gu, Jingyao Zhang
Journal Article
Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft host
Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,
Journal Article
A giant step forward: chimeric antigen receptor T-cell therapy for lymphoma
Houli Zhao, Yiyun Wang, Elaine Tan Su Yin, Kui Zhao, Yongxian Hu, He Huang
Journal Article